7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Synonym(s):7-ADCA

CAS NO.：26395-99-3
Empirical Formula: C8H10N2O3S
Molecular Weight: 214.24
MDL number: MFCD00051489
EINECS: 247-654-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-06-23 18:03:16

7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Structural

What is 7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid?

The Uses of 7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

7-Aminodesacetoxycephalosporanic Acid (Cefadroxil EP Impurity B) is a metabolite of Cephalexin (C256800).

What are the applications of Application

7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (7-ADCA) is an important intermediate for oral cephalosporins, and is mainly used in the synthesis of antibiotics such as cephalosporin, cefadroxil, cefradine, and others.

Properties of 7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Melting point:	>185°C (dec._)
Boiling point:	517.6±50.0 °C(Predicted)
Density	1.59±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Aqueous Base (Slightly), DMSO (Very Slightly, Heated)
form	Solid
pka	3.04±0.50(Predicted)
color	White to Pale Beige
InChI	InChI=1S/C8H10N2O3S/c1-3-2-14-7-4(9)6(11)10(7)5(3)8(12)13/h4,7H,2,9H2,1H3,(H,12,13)

Safety information for 7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChIKey	NVIAYEIXYQCDAN-UHFFFAOYSA-N
SMILES	N12C(C(N)C1=O)SCC(C)=C2C(O)=O

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