6-Methyluracil
Synonym(s):2,4-Dihydroxy-6-methylpyrimidine
- CAS NO.：626-48-2
- Empirical Formula: C5H6N2O2
- Molecular Weight: 126.11
- MDL number: MFCD00006028
- EINECS: 210-949-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:53
What is 6-Methyluracil?
Chemical properties
White to Off-White Crystalline Solid
The Uses of 6-Methyluracil
6-Methyluracil (cas# 626-48-2) is a compound useful in organic synthesis.
Definition
ChEBI: A pyrimidone that is uracil with a methyl group at position 6.
Preparation
6-Methyluracil [626-48-2]. is produced by condensation of diketene with urea. It is used in the production of the analgesic mepirizole, the feed additive orotic acid, and 5-aminoorotic acid.
Safety Profile
Moderately toxic by ingestion. Questionable carcinogen with experimental neoplastigenic and teratogenic data. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
Crystallise 6-methyluracil from EtOH or acetic acid. [Beilstein 24 III/IV 1281.]
Properties of 6-Methyluracil
| Melting point: | 318 °C (dec.)(lit.) |
| Density | 1.226±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | Fine Crystalline Powder |
| pka | pK1:9.52 (25°C) |
| color | White to almost white |
| Water Solubility | 7 g/L (22 ºC) |
| Merck | 14,6133 |
| BRN | 115647 |
| CAS DataBase Reference | 626-48-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 6-Methyluracil(626-48-2) |
| EPA Substance Registry System | 2,4(1H,3H)-Pyrimidinedione, 6-methyl- (626-48-2) |
Safety information for 6-Methyluracil
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H361:Reproductive toxicity |
| Precautionary Statement Codes |
P281:Use personal protective equipment as required. |
Computed Descriptors for 6-Methyluracil
| InChIKey | SHVCSCWHWMSGTE-UHFFFAOYSA-N |
6-Methyluracil manufacturer
JSK Chemicals
3Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 6-Methyluracil, 96% 626-48-2 99%
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