6-Methoxyisoquinoline
- CAS NO.：52986-70-6
- Empirical Formula: C10H9NO
- Molecular Weight: 159.18
- MDL number: MFCD04114861
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:30:12
What is 6-Methoxyisoquinoline?
Chemical properties
Clear Oil
The Uses of 6-Methoxyisoquinoline
6-Methoxy Isoquinoline (cas# 52986-70-6) is a compound useful in organic synthesis.
Preparation
6-Methoxyisoquinoline synthesis: Using benzaldehyde as the starting material, m-methoxybenzaldehyde is obtained through nitration, reduction, diazotization, hydrolysis and methylation, and 3-methoxybenzaldehyde is obtained through condensation with nitromethane Shiff base and reduction of aluminum hydride -p-Phenylethylamine. The Pictet-Spengler reaction of 3-methoxyl-p-phenylethylamine and 40% aqueous formaldehyde produces 6-methoxyl-1,2,3,4-tetrahydroisoquinoline, and then obtains the target compound in dehydrogenation 6-Methoxyisoquinoline.
Synthesis Reference(s)
Journal of the American Chemical Society, 69, p. 1939, 1947 DOI: 10.1021/ja01200a028
Properties of 6-Methoxyisoquinoline
| Boiling point: | 88-95?C/0.8 Torr |
| Density | 1.130±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Dichloromethane |
| form | Oil |
| pka | 6.11±0.10(Predicted) |
| color | Pale Yellow |
| CAS DataBase Reference | 52986-70-6(CAS DataBase Reference) |
Safety information for 6-Methoxyisoquinoline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6-Methoxyisoquinoline
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
![6-methoxyimidazo[1,2-a]pyridine-3-carbaldehyde](https://img.chemicalbook.in/CAS/GIF/944902-87-8.gif)
![IMidazo[1,2-a]pyridine,6-Methoxy-](https://img.chemicalbook.in/CAS/GIF/955376-51-9.gif)
You may like
-
52986-70-6 6-Methoxyisoquinoline, 98% (Custom work) 99%View Details
52986-70-6 -
6-Methoxyisoquinoline 95.00%View Details
52986-70-6 -
144-83-2 Sulfapyridine 98+View Details
144-83-2 -
29976-53-2 98+View Details
29976-53-2 -
6638-79-5 N,O-Dimethylhydroxylamine hydrochloride 98+View Details
6638-79-5 -
674783-97-2 98+View Details
674783-97-2 -
1-Aminocyclopentane carbonitrile 98+View Details
49830-37-7 -
Tetrabutylammonium perchlorate 1923-70-2 98+View Details
1923-70-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.