6-Mercaptohexan-1-ol

Synonym(s):6-Hydroxy-1-hexanethiol;6-MCH;6-Mercaptohexan-1-ol;6-Mercaptohexanol;MCH

CAS NO.：1633-78-9
Empirical Formula: C6H14OS
Molecular Weight: 134.24
MDL number: MFCD00068552
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-24 14:58:30

What is 6-Mercaptohexan-1-ol?

Chemical properties

Colorless to light yellow liquid

The Uses of 6-Mercaptohexan-1-ol

6-Mercapto-1-hexanolcan be used as a chemical linker for anchoring biological molecules to gold surfaces.

The Uses of 6-Mercaptohexan-1-ol

This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with alcohols can be further functionalized with various groups even when attached to gold nanoclusters.

The Uses of 6-Mercaptohexan-1-ol

MCH is coated on a piezoelectric crystal which can be used for the fabrication of chemical sensor to differentiate between cheese varieties. Self assembled monolayers of MCH can be used on gold surfaces for bio-sensing applications. It can also be used as a monolayer for the surface modification of gold-polyaniline (Au-PANI) nanocomposites for the development of aptamer based biosensors (aptasensors).

General Description

6-mecapto-1-hexanol (MCH) forms a self-assembled monolayer (SAM) with identically represented C6 spacer. MCH is a tool for surface coating that enables blocking of active sites and non-specific absorption.

Properties of 6-Mercaptohexan-1-ol

Boiling point:	225 °C(lit.)
Density	0.981 g/mL at 25 °C(lit.)
refractive index	n20/D 1.486(lit.)
Flash point:	>230 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	liquid
pka	10.47±0.10(Predicted)
color	Colourless
BRN	1846871
Stability:	Air Sensitive
InChI	InChI=1S/C6H14OS/c7-5-3-1-2-4-6-8/h7-8H,1-6H2
EPA Substance Registry System	1-Hexanol, 6-mercapto- (1633-78-9)

Safety information for 6-Mercaptohexan-1-ol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.