6-Hydroxyindole

Synonym(s):6-Indolol

White to off-white shiny crystalline powder

Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
Reactant for asymmetrical synthesis of notoamide J as a potential biosynthetic precursor of prenylated indole alkaloids
Reactant for preparation of (quinolinyloxymethyl)isoxazolecarboxylate esters antituberculosis agents
Reactant for preparation of indolyl(propanolamine) derivatives as HIV inhibitors
Reactant for preparation of indoleoxyacetic acid derivatives as peroxisome proliferator-activated receptor agonists
Reactant for preparation of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors

6-Hydroxyindole is a reactant for asymmetrical synthesis of notoamide J

Journal of Medicinal Chemistry, 35, p. 2419, 1992 DOI: 10.1021/jm00091a010

Melting point:	125-128 °C
Boiling point:	343.2±15.0 °C(Predicted)
Density	1.327±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	Chloroform (Slightly, Heated), Methanol (Slightly)
pka	10.07±0.40(Predicted)
form	Shiny Crystalline Powder
color	White to off-white
CAS DataBase Reference	2380-86-1(CAS DataBase Reference)

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.