6-Bromo-1,3-dihydro-2H-indol-2-one
- CAS NO.：99365-40-9
- Empirical Formula: C8H6BrNO
- Molecular Weight: 212.04
- MDL number: MFCD02179605
- EINECS: 800-899-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:03
What is 6-Bromo-1,3-dihydro-2H-indol-2-one?
Chemical properties
Light yelllow crystal
The Uses of 6-Bromo-1,3-dihydro-2H-indol-2-one
6-Bromo-2-Oxindole is an indolinone derivative used for the preparation of p38α inhibitors as potential antiinflammatories.
The Uses of 6-Bromo-1,3-dihydro-2H-indol-2-one
6-Bromooxindole derivative is used in the preparation of p38alpha inhibitors as potential anti- inflammatories. It is used as an intermediate in pharmaceuticals.
Properties of 6-Bromo-1,3-dihydro-2H-indol-2-one
| Melting point: | 217-221 °C(lit.) |
| Boiling point: | 343.6±42.0 °C(Predicted) |
| Density | 1.666±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSo |
| form | Solid |
| pka | 13.39±0.20(Predicted) |
| color | Orange |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 99365-40-9(CAS DataBase Reference) |
Safety information for 6-Bromo-1,3-dihydro-2H-indol-2-one
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08  Environment GHS09 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H341:Germ cell mutagenicity H361:Reproductive toxicity H371:Specific target organ toxicity, single exposure H372:Specific target organ toxicity, repeated exposure H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P391:Collect spillage. Hazardous to the aquatic environment P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. |
Computed Descriptors for 6-Bromo-1,3-dihydro-2H-indol-2-one
| InChIKey | JARRYVQFBQVOBE-UHFFFAOYSA-N |
6-Bromo-1,3-dihydro-2H-indol-2-one manufacturer
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