6-AMINOISOQUINOLINE
- CAS NO.：23687-26-5
- Empirical Formula: C9H8N2
- Molecular Weight: 144.17
- MDL number: MFCD04114862
- EINECS: 639-440-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:16:22
What is 6-AMINOISOQUINOLINE?
Description
6-Aminoisoquinoline is an organosynthetic intermediate used in the preparation of Netarsudil, which is a drug used in the treatment and management of glaucoma and high intraocular pressure.
The Uses of 6-AMINOISOQUINOLINE
6-Aminoisoquinoline is a reactant used in the preparation of N-[{2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)-pyridin-3-yl}methyl] N''-(6,6-fused heterocyclic) ureas as highly potent TRPV1 antagonists.
Properties of 6-AMINOISOQUINOLINE
| Melting point: | 211-212 °C(Solv: benzene (71-43-2)) |
| Boiling point: | 343.1±15.0 °C(Predicted) |
| Density | 1.210±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMF (Slightly), DMSO (Sparingly), Methanol (Slightly) |
| pka | 7.10±0.10(Predicted) |
| color | Light yellow to yellow |
Safety information for 6-AMINOISOQUINOLINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. |
Computed Descriptors for 6-AMINOISOQUINOLINE
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