5(S)-HETE-D8
- CAS NO.：330796-62-8
- Empirical Formula: C20H24D8O3
- Molecular Weight: 328.52
- MDL number: MFCD00084826
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is 5(S)-HETE-D8?
The Uses of 5(S)-HETE-D8
5(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 5(S)-HETE by GC- or LC-mass spectrometry (MS). 5(S)-HETE is produced by the action of 5-lipoxygenase on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to the 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4.
What are the applications of Application
5(S)-HETE-d8 is an internal standard for the quantification of 5(S)-HETE by GC or LC-mass spectrometry
Properties of 5(S)-HETE-D8
| storage temp. | Store at -20°C |
| solubility | 0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml |
Safety information for 5(S)-HETE-D8
Computed Descriptors for 5(S)-HETE-D8
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