5-O-Desmethyl Donepezil
- CAS NO.：120013-57-2
- Empirical Formula: C23H27NO3
- Molecular Weight: 365.47
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:17
What is 5-O-Desmethyl Donepezil?
Chemical properties
Off-White Solid
The Uses of 5-O-Desmethyl Donepezil
A metabolite of Donepezil, an inhibitor of acetylcholinesterase
The Uses of 5-O-Desmethyl Donepezil
A metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.
What are the applications of Application
5-O-Desmethyl Donepezil is an inhibitor of acetylcholinesterase (AChE)
Definition
ChEBI: 5-O-desmethyldonepezil is a member of the class of piperidines that is donepezil in which the 5-methoxy group has been demethylated to the corresponding hydroxy derivative. It is metabolite of donepezil, a drug used in the treatment of dementia. It has a role as a drug metabolite. It is a member of piperidines, a cyclic ketone, an aromatic ether and a member of guaiacols.
Properties of 5-O-Desmethyl Donepezil
| Melting point: | 170-172°C |
| Boiling point: | 545.3±50.0 °C(Predicted) |
| Density | 1.190±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated) |
| pka | 8.16±0.40(Predicted) |
| form | Solid |
| color | White to Pale Brown |
| CAS DataBase Reference | 120013-57-2 |
Safety information for 5-O-Desmethyl Donepezil
Computed Descriptors for 5-O-Desmethyl Donepezil
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