5-Methylcytidine

CAS NO.：2140-61-6
Empirical Formula: C10H15N3O5
Molecular Weight: 257.24
MDL number: MFCD00006548
EINECS: 218-390-8
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-13 13:05:00

What is 5-Methylcytidine?

Chemical properties

White powder

The Uses of 5-Methylcytidine

5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.

The Uses of 5-Methylcytidine

5-Methylcytidine is used in studies of DNA methylation processes (epigenetics).

What are the applications of Application

5-Methylcytidine is a derivative of Cytidine

Definition

ChEBI: 5-methylcytidine is a methylcytidine.

General Description

5-Methylcytidine is a component of RNA in Escherichia coli. It is present in the RNA of plant, animal and bacterial origin. It is one of the C derivative present in transfer RNA (tRNA).

Biochem/physiol Actions

5-Methylcytidine is an alkylated pyrimidine plays an important role enhancing the stacking in A- and B- helices of nucleic acid, results in increase of the melting temperature and improves thermal stability leading to structural stabilization.

Properties of 5-Methylcytidine

Melting point:	212-215 °C (dec.) (lit.)
Boiling point:	537.5±60.0 °C(Predicted)
Density	1.79
refractive index	15 ° (C=2, H2O)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
pka	pK1:4.21 (25°C)
form	Solid
color	Off-White to Pale Beige
Stability:	Hygroscopic
CAS DataBase Reference	2140-61-6(CAS DataBase Reference)