5-Methylcytidine
- CAS NO.：2140-61-6
- Empirical Formula: C10H15N3O5
- Molecular Weight: 257.24
- MDL number: MFCD00006548
- EINECS: 218-390-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-12 18:10:29
What is 5-Methylcytidine?
Chemical properties
White powder
The Uses of 5-Methylcytidine
5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.
The Uses of 5-Methylcytidine
5-Methylcytidine is used in studies of DNA methylation processes (epigenetics).
What are the applications of Application
5-Methylcytidine is a derivative of Cytidine
Definition
ChEBI: 5-methylcytidine is a methylcytidine.
General Description
5-Methylcytidine is a component of RNA in Escherichia coli. It is present in the RNA of plant, animal and bacterial origin. It is one of the C derivative present in transfer RNA (tRNA).
Biochem/physiol Actions
5-Methylcytidine is an alkylated pyrimidine plays an important role enhancing the stacking in A- and B- helices of nucleic acid, results in increase of the melting temperature and improves thermal stability leading to structural stabilization.
Properties of 5-Methylcytidine
| Melting point: | 212-215 °C (dec.) (lit.) |
| Boiling point: | 537.5±60.0 °C(Predicted) |
| Density | 1.79 |
| refractive index | 15 ° (C=2, H2O) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Sparingly) |
| pka | pK1:4.21 (25°C) |
| form | Solid |
| color | Off-White to Pale Beige |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 2140-61-6(CAS DataBase Reference) |
Safety information for 5-Methylcytidine
Computed Descriptors for 5-Methylcytidine
| InChIKey | ZAYHVCMSTBRABG-JXOAFFINSA-N |
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