5-METHYL-DL-TRYPTOPHAN
- CAS NO.:951-55-3
- Empirical Formula: C12H14N2O2
- Molecular Weight: 218.25
- MDL number: MFCD00005652
- EINECS: 213-453-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:06
What is 5-METHYL-DL-TRYPTOPHAN?
Chemical properties
off-white powder
What are the applications of Application
5-Methyl-DL-tryptophan is a corepressor of the E. coli trp repressor
Definition
ChEBI: 5-methyltryptophan is a tryptophan derivative that is tryptophan substituted by a methyl group at position 5 of the indole ring. It is a non-proteinogenic alpha-amino acid and a tryptophan derivative.
Purification Methods
Crystallise dl-5-methyltryptophan from aqueous EtOH after dissolving it in aqueous NaOH, precipitating with AcOH, filtering the solid off and drying for 24hours at 50o. [Jackman & Archer J Am Chem Soc 68 2105 1946, Beilstein 22 IV 6815.] The picrate crystallises from MeOH with m 202o(dec). The N-phenylcarbamoyl derivative crystallises from aqueous MeOH with m 202o. [Gordon & Jackson J Biol Chem 110 151, 154 1935.]
Properties of 5-METHYL-DL-TRYPTOPHAN
| Melting point: | ~275 °C (dec.) |
| Boiling point: | 358.94°C (rough estimate) |
| alpha | [α]D20 -1~+1゜ (c=1, dil. HCl) |
| Density | 1.1402 (rough estimate) |
| refractive index | 1.6660 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 2.26±0.10(Predicted) |
| form | Powder |
| color | Off-white |
| BRN | 20225 |
| CAS DataBase Reference | 951-55-3(CAS DataBase Reference) |
Safety information for 5-METHYL-DL-TRYPTOPHAN
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 5-METHYL-DL-TRYPTOPHAN
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile BudesonideRelated products of tetrahydrofuran








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