5-METHYL-2-NITROANILINE

Synonym(s):6-Nitro-m-toluidine

5-Methyl-2-nitroaniline has been used in the preparation of N-(5-methyl-2-nitrophenyl)-4-[N-(pyridin-3-ylmethoxy carbonyl)aminomethyl]benzamide.

The Journal of Organic Chemistry, 45, p. 4992, 1980 DOI: 10.1021/jo01312a039

Yellow leaflets (from water) or orange powder.

5-METHYL-2-NITROANILINE is sensitive to prolonged exposure to air. Insoluble in water.

5-METHYL-2-NITROANILINE is incompatible with acids, acid chlorides, acid anhydrides, chloroformates, and strong oxidizers .

SYMPTOMS: Symptoms of exposure to 5-METHYL-2-NITROANILINE may include irritation. Structurally similar chemicals may cause methemoglobinemia.

Flash point data for 5-METHYL-2-NITROANILINE are not available; however, 5-METHYL-2-NITROANILINE is probably combustible.

Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx.

Melting point:	110-111 °C (lit.)
Boiling point:	312.4±22.0 °C(Predicted)
Density	1.269±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	0.03±0.25(Predicted)
BRN	2691416
CAS DataBase Reference	578-46-1(CAS DataBase Reference)
EPA Substance Registry System	5-Methyl-2-nitroaniline (578-46-1)

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell.