5-Methyl-1H-pyrazole-3-carboxylic acid
Synonym(s):5-Methylpyrazole-3-carboxylic acid;AS057278;MPC
- CAS NO.：402-61-9
- Empirical Formula: C5H6N2O2
- Molecular Weight: 126.11
- MDL number: MFCD00090754
- EINECS: 673-162-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:28:42
What is 5-Methyl-1H-pyrazole-3-carboxylic acid?
Chemical properties
White to light yellow solid
The Uses of 5-Methyl-1H-pyrazole-3-carboxylic acid
3-Methylpyrazole-5-carboxylic acid is a potent and selective D-amino acid oxidase (DAO) (also known as DAAO, DAMOX and OXDA) inhibitor that protects DAO cells from oxidative stress induced by D-Serine. 3-Methylpyrazole-5-carboxylic acid specifically prevents formalin-induced tonic pain.
What are the applications of Application
3-Methylpyrazole-5-carboxylic acid is a potent and selective D-amino acid oxidase inhibitor
Definition
ChEBI: A memebr of the class of pyrazoles that is 1H-pyrazole with methyl and carboxylic acid group substituents at positions 5 and 3 respectively.
General Description
3-Methylpyrazole-5-carboxylic acid is a potent and selective D-amino acid oxidase (DAO) (also known as DAAO, DAMOX and OXDA) inhibitor that protects DAO cells from oxidative stress induced by D-Serine. 3-Methylpyrazole-5-carboxylic acid specifically prevents formalin-induced tonic pain.
Properties of 5-Methyl-1H-pyrazole-3-carboxylic acid
| Melting point: | 241 °C |
| Boiling point: | 388.8±22.0 °C(Predicted) |
| Density | 1.404±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in dimethyl sulfoxide. |
| form | powder to crystal |
| pka | 15.36±0.10(Predicted) |
| color | White to Yellow to Orange |
| CAS DataBase Reference | 402-61-9(CAS DataBase Reference) |
Safety information for 5-Methyl-1H-pyrazole-3-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 5-Methyl-1H-pyrazole-3-carboxylic acid
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