5-Fluoroindole

Chemical properties

off-white crystalline powder

The Uses of 5-Fluoroindole

5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3.

The Uses of 5-Fluoroindole

• ;Reactant for preparation of 5-HT6 receptor ligands1• ;Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Reactant for preparation of antitumor agents3• ;Reactant for preparation of antibacterial agents4• ;Reactant for preparation of immunosuppressive agents5• ;Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes6• ;Reactant for preparation of Myeloperoxidase Inhibitors7• ;Reactant fo

The Uses of 5-Fluoroindole

• Reactant for preparation of 5-HT6 receptor ligands
• Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Reactant for preparation of antitumor agents
• Reactant for preparation of antibacterial agents
• Reactant for preparation of immunosuppressive agents
• Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes
• Reactant for preparation of Myeloperoxidase Inhibitors
• Reactant for preparation of Potent Selective Serotonin Reuptake Inhibitors

Definition

ChEBI: An organofluorine compound that is the 5-fluoro derivative of indole.