5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
- CAS NO.：1363380-51-1
- Empirical Formula: C6H3ClN4O2
- Molecular Weight: 198.57
- MDL number: MFCD22415211
- EINECS: 251-228-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-05-08 09:45:22
![5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Structural](https://img.chemicalbook.in/CAS/GIF/1363380-51-1.gif)
What is 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine?
The Uses of 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine is used in the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, a tyrosine kinase (TRK) inhibitor for treating cancer.
Properties of 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
| Melting point: | 163 - 165°C |
| Density | 1.85±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly, Heated), DMSO (Slightly) |
| form | Solid |
| pka | -3.59±0.40(Predicted) |
| color | Purple |
Safety information for 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine manufacturer
GK Chemicals
1Y
Phone:+91-7207279444
Whatsapp: +91-7207279444
product: 5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 1363380-51-1 98%
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