5-CHLORO-2-NITROANISOLE
- CAS NO.：6627-53-8
- Empirical Formula: C7H6ClNO3
- Molecular Weight: 187.58
- MDL number: MFCD00007288
- EINECS: 229-594-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:13:47
What is 5-CHLORO-2-NITROANISOLE?
Chemical properties
SLIGHTLY YELLOW TO GREEN CRYSTALLINE POWDER
The Uses of 5-CHLORO-2-NITROANISOLE
5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs. In addition it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells.
The Uses of 5-CHLORO-2-NITROANISOLE
5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs (1). In addition, it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells (2).
Properties of 5-CHLORO-2-NITROANISOLE
| Melting point: | 70-72 °C(lit.) |
| Boiling point: | 289.1±20.0 °C(Predicted) |
| Density | 1.4219 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Ethyl Acetate |
| form | Solid |
| color | Yellow |
| CAS DataBase Reference | 6627-53-8(CAS DataBase Reference) |
| EPA Substance Registry System | 5-Chloro-2-nitroanisole (6627-53-8) |
Safety information for 5-CHLORO-2-NITROANISOLE
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 5-CHLORO-2-NITROANISOLE
5-CHLORO-2-NITROANISOLE manufacturer
SAKEM LLP
1Y
Phone:+91-9676889998
Whatsapp: +91-9676889998
product: 5-Chloro-2-nitroanisole 6627-53-8 98%
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