5-Bromo-5-nitro-1,3-dioxane

CAS NO.：30007-47-7
Empirical Formula: C4H6BrNO4
Molecular Weight: 212
MDL number: MFCD00101855
EINECS: 250-001-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-28 15:00:41

What is 5-Bromo-5-nitro-1,3-dioxane?

Description

5-Bromo-5-nitro-1,3-dioxane, also known as , exhibits antimicrobial properties against a wide range of microorganisms including gram-negative and gram-positive bacteria, yeast, and fungi. Bronidox is commonly employed as a stabilizer and preservative in biological molecules and solutions, such as antibodies and antisera. It finds application in rinse-off cosmetics, where it serves as a preserving agent. Bronidox can be used alone or in combination with methylisothiazolone to enhance its effectiveness.

Chemical properties

White solid

The Uses of 5-Bromo-5-nitro-1,3-dioxane

5-Bromo-5-nitro-1,3-dioxane is used as a stabilizer and preserving agent for biological molecules and solutions such as antibodies and antisera. Bronidox is used in a variety of rinse-off cosmetic. It can be used alone or in combination with methylisothiazolone.

What are the applications of Application

5-Bromo-5-nitro-1,3-dioxane is An antibacterial agent.

General Description

5-Bromo-5-nitro-1,3-dioxane is a bromine containing preservative commonly used in cosmetic products.

Flammability and Explosibility

Not classified

Properties of 5-Bromo-5-nitro-1,3-dioxane

Melting point:	58-60 °C
Boiling point:	280.8±40.0 °C(Predicted)
Density	1.070
vapor pressure	1.6Pa at 20℃
refractive index	1.6200 (estimate)
storage temp.	2-8°C
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml; Ethanol: 25 mg/ml
form	Solid
form	neat
color	White to Almost white
Water Solubility	Soluble in water at 12.5mg/ml
InChI	InChI=1S/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2
CAS DataBase Reference	30007-47-7(CAS DataBase Reference)
NIST Chemistry Reference	1,3-Dioxane, 5-bromo-5-nitro-(30007-47-7)
EPA Substance Registry System	1,3-Dioxane, 5-bromo-5-nitro- (30007-47-7)

Safety information for 5-Bromo-5-nitro-1,3-dioxane

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H314:Skin corrosion/irritation H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.