4,6-DIMETHOXYSALICYLALDEHYDE
Synonym(s):2,4-Dimethoxy-6-hydroxybenzaldehyde;4,6-Dimethoxy-2-hydroxybenzaldehyde
- CAS NO.：708-76-9
- Empirical Formula: C9H10O4
- Molecular Weight: 182.17
- MDL number: MFCD00003328
- EINECS: 211-904-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:48
What is 4,6-DIMETHOXYSALICYLALDEHYDE?
Chemical properties
yellow to beige crystalline powder
The Uses of 4,6-DIMETHOXYSALICYLALDEHYDE
4,6-Dimethoxysalicylaldehyde was used in the preparation of a new class of efficient ketocoumarin triplet sensitizers. It was used as staring reagent in the total synthesis of (+/-)-linderol A, a hexahydrodibenzofuran.
What are the applications of Application
4,6-Dimethoxysalicylaldehyde is a useful antifungal against certain yeasts and a precursor to hexahydrodibenzofuran
General Description
4,6-Dimethoxysalicylaldehyde on condensation with methylamine yields Schiff bases.
Biochem/physiol Actions
4,6-Dimethoxysalicylaldehyde has antimicrobial activity against Candida albicans.
Properties of 4,6-DIMETHOXYSALICYLALDEHYDE
| Melting point: | 68-70 °C (lit.) |
| Boiling point: | 131°C/0.05mmHg(lit.) |
| Density | 1.2481 (rough estimate) |
| refractive index | 1.4500 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 7.42±0.15(Predicted) |
| color | White to Light yellow to Light orange |
| BRN | 1241679 |
| CAS DataBase Reference | 708-76-9(CAS DataBase Reference) |
Safety information for 4,6-DIMETHOXYSALICYLALDEHYDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4,6-DIMETHOXYSALICYLALDEHYDE
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloropyridazine 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 6-Methyl-2-pyridinemethanol 2-Pyridinecarboxaldehdye tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 1-Indanone 2-Chloromethyl-6-methyl-pyridine 4-Morpholinoaniline Abiraterone Ethyl Ether 1-nitro-3,5-dimethyl adamantine (NMEM) Vardenafil Bis-sulphonamide(Dimer) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
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