4,5-DIBROMO-O-XYLENE
Synonym(s):4,5-Dibromo-o-xylene
- CAS NO.：24932-48-7
- Empirical Formula: C8H8Br2
- Molecular Weight: 263.96
- MDL number: MFCD00082743
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-08 17:45:00
What is 4,5-DIBROMO-O-XYLENE?
Chemical properties
White solid
The Uses of 4,5-DIBROMO-O-XYLENE
1,2-Dibromo-4,5-dimethylbenzene is used as a reagent in the synthesis of Thalidomide (T338850); an inhibitor of FGF-induced angiogenesis and replication of human immunodeficiency virus type 1. Also a teratogenic sedative and immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
The Uses of 4,5-DIBROMO-O-XYLENE
1,2-Dibromo-4,5-dimethylbenzene can be used in the synthesis of alkylamino zinc(II)phthalocyanines, with potential application as photosensitizers in photodynamic therapy. It can also be used in the synthesis of 1,2-dibromo-4,5-bis(dibromomethyl)benzene via reaction with azobisisobutyronitrile.
General Description
1,2-Dibromo-4,5-dimethylbenzene can be synthesized via bromination of o-xylene.
Properties of 4,5-DIBROMO-O-XYLENE
| Melting point: | 85-89 °C (lit.) |
| Boiling point: | 278 °C |
| Density | 1.7485 (rough estimate) |
| refractive index | 1.6146 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Pale Yellow |
| BRN | 2206183 |
| CAS DataBase Reference | 24932-48-7(CAS DataBase Reference) |
Safety information for 4,5-DIBROMO-O-XYLENE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4,5-DIBROMO-O-XYLENE
| InChIKey | BCIDDURGCAHERU-UHFFFAOYSA-N |
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