4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
Synonym(s):14-norlanosterol; 4,4-dimethylzymosterol; T-MAS; 110892;4,4-dimethylcholest-8(9),24-dien-3β-ol
- CAS NO.：7448-02-4
- Empirical Formula: C29H48O
- Molecular Weight: 412.69
- MDL number: MFCD00945030
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:41
What is 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol?
The Uses of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
14-Norlanosterol, is a metabolite of Lanosterol (L174580). It is also a meiosis activating sterol (MAS), which is shown to have an important role in regulating meiosis and reproduction.
The Uses of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
14-demethyl-lanosterol has been used to reduce cancer cell viability and increase cancer cell sensitivity to erlotinib.
Definition
ChEBI: A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol.
General Description
14-demethyl-lanosterol acts as an intermediate in cholesterol biosynthesis. It is used to stimulate oocytes for meiosis. 14-demethyl-lanosterol modulates cumulus expansion.
Properties of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
| storage temp. | -70°C |
Safety information for 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
Computed Descriptors for 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
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