4'-Piperidinoacetophenone
Synonym(s):1-[4-(1-Piperidinyl)]phenyl]ethanone
- CAS NO.：10342-85-5
- Empirical Formula: C13H17NO
- Molecular Weight: 203.28
- MDL number: MFCD00006481
- EINECS: 233-746-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:22
What is 4'-Piperidinoacetophenone?
Chemical properties
yellow flakes
The Uses of 4'-Piperidinoacetophenone
Pharmacological activity:
- Selective antimycobacterial activity
- Bronchodilator compound
- Modulation of flagellar motility in Chlamydomonas
General Description
4′-Piperidinoacetophenone undergoes Claisen-Schmidt condensation with substituted benzaldehydes using NaOH-Al2O3 by microwave irradiation to give chalcones. It has antimycobacterial activity.
Properties of 4'-Piperidinoacetophenone
| Melting point: | 85-87 °C (lit.) |
| Boiling point: | 341.6°C (rough estimate) |
| Density | 1.0156 (rough estimate) |
| refractive index | 1.5400 (estimate) |
| storage temp. | 2-8°C |
| pka | 3.59±0.20(Predicted) |
| CAS DataBase Reference | 10342-85-5(CAS DataBase Reference) |
| EPA Substance Registry System | 4'-Piperidinoacetophenone (10342-85-5) |
Safety information for 4'-Piperidinoacetophenone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4'-Piperidinoacetophenone
New Products
2-Amino-5-bromo-4-(trifluoromethyl)pyridine Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde β-Bromostyrene Ethyl 3-phenylpropanoate Phenethyl cinnamate Dipropyl disulfide N-Vinylformamide 4 pentyn 1 ol Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
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