4-Phenylmorpholine
Synonym(s):Morpholinobenzene;N-Phenylmorpholine
- CAS NO.：92-53-5
- Empirical Formula: C10H13NO
- Molecular Weight: 163.22
- MDL number: MFCD00006166
- EINECS: 202-164-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:58
What is 4-Phenylmorpholine?
Chemical properties
white to brownish crystalline solid
The Uses of 4-Phenylmorpholine
4-Phenylmorpholine was used as internal standard during the determination of alkaloids by gas chromatographic method.
Synthesis Reference(s)
The Journal of Organic Chemistry, 50, p. 1365, 1985 DOI: 10.1021/jo00209a004
General Description
4-Phenylmorpholine undergoes oxidation to yield N-formyl-N-2-hydroxyethylaniline.
Safety Profile
Poison by skin contact. Moderately toxic by ingestion. An eye irritant. When heated to decomposition it emits toxic fumes of NOx.
Properties of 4-Phenylmorpholine
| Melting point: | 51-54 °C(lit.) |
| Boiling point: | 165-170 °C45 mm Hg(lit.) |
| Density | 1.053 g/cm3 (60℃) |
| vapor density | 5.63 (vs air) |
| vapor pressure | <0.1 mm Hg ( 20 °C) |
| refractive index | 1.5400 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | 3.46 g/L |
| pka | 5.19±0.40(Predicted) |
| form | powder to crystal |
| color | White to Light yellow to Light red |
| Water Solubility | 3.46 g/L |
| CAS DataBase Reference | 92-53-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Morpholine, 4-phenyl-(92-53-5) |
| EPA Substance Registry System | Morpholine, 4-phenyl- (92-53-5) |
Safety information for 4-Phenylmorpholine
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H311:Acute toxicity,dermal |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
Computed Descriptors for 4-Phenylmorpholine
| InChIKey | FHQRDEDZJIFJAL-UHFFFAOYSA-N |
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