4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
- CAS NO.：21561-09-1
- Empirical Formula: C16H15N3O2
- Molecular Weight: 281.31
- MDL number: MFCD01815294
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE?
Description
WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.
The Uses of 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3).
Properties of 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
| Boiling point: | 441.2±40.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml |
| form | A crystalline solid |
| pka | 6.19±0.70(Predicted) |
| color | White to off-white |
Safety information for 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
Computed Descriptors for 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
New Products
Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
![Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-](https://img.chemicalbook.in/CAS/20150408/GIF/211555-08-7.gif)
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