4-NONYLPHENOL

Synonym(s):p-n-Nonylphenol;4-n-Nonylphenol

CAS NO.：104-40-5
Empirical Formula: C15H24O
Molecular Weight: 220.35
MDL number: MFCD00002396
EINECS: 203-199-4
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-10 10:27:31

What is 4-NONYLPHENOL?

Chemical properties

viscous colourless liquid with a phenol-like smell

The Uses of 4-NONYLPHENOL

4-nonylphenol is used in the process for the manufacture of 5-nonyl salicylaldoxime, which is used for the selective purification and concentration of copper ions.

The Uses of 4-NONYLPHENOL

weevil pheromone, shows estrogenic activity

The Uses of 4-NONYLPHENOL

Principal use as an intermediate in the production of nonionic ethoxylated surfactants; as an intermediate in the manufacture of phosphite antioxidants used for the plastics and rubber industries

Definition

ChEBI: A member of the class of phenols that is phenol which is para-substituted with a nonyl group.

Health Hazard

Nonylphenol is a severe irritant of the eyes and skin.

Carcinogenicity

Nonylphenol has recently been shown to have estrogenic properties, triggering mitotic activity in rat endometrium and cell proliferation in estrogen-sensitive tumor cells.9 Potential toxicity to humans who may be exposed to nonylphenol through leaching of plastics has not been determined.

Properties of 4-NONYLPHENOL

Melting point:	43-44°C
Boiling point:	293-297 °C
Density	0.937 g/mL at 25 °C(lit.)
vapor pressure	0.109Pa at 25℃
refractive index	n20/D 1.511(lit.)
Flash point:	>230 °F
storage temp.	APPROX 20°C
solubility	Sparingly Soluble (0.020 g/L) at 25°C.
form	neat
pka	10.15±0.15(Predicted)
color	Clear colorless
Specific Gravity	~1.057
Odor	Phenol like
PH Range	6 - 8
Water Solubility	6.35mg/L(25 ºC)
BRN	2047450
Dielectric constant	5.2000000000000002
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	104-40-5(CAS DataBase Reference)
EPA Substance Registry System	p-Nonylphenol (104-40-5)

Safety information for 4-NONYLPHENOL

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H314:Skin corrosion/irritation H361:Reproductive toxicity H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.