4-Nitrosalicylic acid

Synonym(s):2-Hydroxy-4-nitrobenzoic acid

CAS NO.：619-19-2
Empirical Formula: C7H5NO5
Molecular Weight: 183.12
MDL number: MFCD00071505
EINECS: 210-584-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:19:56

What is 4-Nitrosalicylic acid?

Chemical properties

White to yellow crystalline powder

The Uses of 4-Nitrosalicylic acid

4-Nitrosalicylic Acid is a metabolite in the degradation pathway of 2-chloro-4-nitrobenzoic acid by acinetobacter strain RKJ12.

The Uses of 4-Nitrosalicylic acid

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

What are the applications of Application

2-Hydroxy-4-nitrobenzoic acid is metabolized to 2,4-dihydroxybenzoic acid (2,4-DHBA) by a mono-oxygenase with the concomitant release of chloride and nitrite ions

General Description

2-Hydroxy-4-nitrobenzoic acid is metabolized to 2,4-dihydroxybenzoic acid (2,4-DHBA) by a mono-oxygenase with the concomitant release of chloride and nitrite ions.

Safety Profile

Poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.

Properties of 4-Nitrosalicylic acid

Melting point:	235-239 °C (lit.)
Boiling point:	316.77°C (rough estimate)
Density	1.6074 (rough estimate)
refractive index	1.6280 (estimate)
storage temp.	Sealed in dry,Room Temperature
form	Solid or Crystalline Powder
pka	2.11±0.13(Predicted)
color	White to pale brown
CAS DataBase Reference	619-19-2(CAS DataBase Reference)
EPA Substance Registry System	Benzoic acid, 2-hydroxy-4-nitro- (619-19-2)

Safety information for 4-Nitrosalicylic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.