4-Nitropyrazole-3-carboxylic acid

CAS NO.：5334-40-7
Empirical Formula: C4H3N3O4
Molecular Weight: 157.08
MDL number: MFCD00090899
EINECS: 605-126-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 06:15:41

What is 4-Nitropyrazole-3-carboxylic acid?

Chemical properties

White to off-white crystalline powder

The Uses of 4-Nitropyrazole-3-carboxylic acid

4-Nitro-1H-pyrazole-3-carboxylic Acid, is a building block used for the synthesis of biologically active compounds. It is an intermediate for the synthesis of pyrazole-benzimidazole derivatives as potent Aurora A/B kinase inhibitors.

The Uses of 4-Nitropyrazole-3-carboxylic acid

4-Nitro-3-pyrazolecarboxylic acid may be used as a starting reagent for the synthesis of library of pyrazole derivatives, potential A₃ adenosine receptor (A₃AR) antagonists.

General Description

4-Nitro-3-pyrazolecarboxylic acid is a pyrazole derivative. Catalytic activity of bimetallic colloids, composed of silver nanoparticles partially coated with Pd clusters, adsorbed on 4-nitro-3-pyrazolecarboxylic acid, has been investigated by Surface-enhanced Raman scattering (SERS) spectroscopy. Effects of this pyrrazole on blood flow and its palladium hydrogenation has been studied.

Properties of 4-Nitropyrazole-3-carboxylic acid

Melting point:	195°C
Boiling point:	509.6±35.0 °C(Predicted)
Density	1.840±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	1.41±0.35(Predicted)
color	Cream
CAS DataBase Reference	5334-40-7(CAS DataBase Reference)

Safety information for 4-Nitropyrazole-3-carboxylic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.