4-Methyl-5-thiazolylethyl acetate

Synonym(s):4-Methyl-5-thiazolylethyl acetate;Sulfurol acetate;Sulfuryl acetate

CAS NO.：656-53-1
Empirical Formula: C8H11NO2S
Molecular Weight: 185.24
MDL number: MFCD00005338
EINECS: 211-515-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-03 14:17:14

4-Methyl-5-thiazolylethyl acetate Structural

What is 4-Methyl-5-thiazolylethyl acetate?

Description

May be prepared from 2-methylthio-4-methyl-5-(2-acetoxyethyl)- thiazole and AlHg; by dehydrogenation with sulfur at 130°C of the (i-acetyl derivative of 4-methyl-5-(P-hydroxyethyl)-3-thiazoline.

Chemical properties

Colorless to light yellow liqui

Chemical properties

4-Methyl-5-thiazoleethanol acetate has an odor reminiscent of meat.

The Uses of 4-Methyl-5-thiazolylethyl acetate

4-Methyl-5-thiazolylethyl Acetate is used in biological study for research on contribution of oxidized tallow to aroma characteristics of beeflike process flavor assessed by gas chromatography-mass spectrometry and partial least squares regression.

Preparation

From 2-methylthio-4-methyl-5-(2-acetohxyethyl)-thiazole and AlHg; by dehydrogenation with sulfur at 130°C of the β-acetyl derivative of 4-methyl-5-(β-hydroxyethyl)-3-thiazoline

Definition

ChEBI: 5-(2-Hydroxyethyl)-4-methylthiazole acetate is a member of thiazoles.

Taste threshold values

Taste characteristics at 10 ppm: meaty, brothy, bready and brown with a beefy, bloody and chicken note.

Properties of 4-Methyl-5-thiazolylethyl acetate

Melting point:	112 °C
Boiling point:	117-118 °C6 mm Hg(lit.)
Density	1.147 g/mL at 25 °C(lit.)
refractive index	n20/D 1.51(lit.)
FEMA	3205 \| 4-METHYL-5-THIAZOLEETHANOL ACETATE
Flash point:	>230 °F
storage temp.	2-8°C
form	Liquid
pka	3.26±0.10(Predicted)
Specific Gravity	1.147
color	Clear brown
Odor	at 100.00 %. meaty beef juice beef gravey
JECFA Number	1054
CAS DataBase Reference	656-53-1(CAS DataBase Reference)
EPA Substance Registry System	5-Thiazoleethanol, 4-methyl-, acetate (ester) (656-53-1)

Safety information for 4-Methyl-5-thiazolylethyl acetate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.