4-Methoxyphenethylamine
Synonym(s):2-(4-Methoxyphenyl)ethylamine;4-Methoxyphenethylamine
- CAS NO.:55-81-2
- Empirical Formula: C9H13NO
- Molecular Weight: 151.21
- MDL number: MFCD00008192
- EINECS: 200-245-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-11-24 17:44:56
What is 4-Methoxyphenethylamine ?
Chemical properties
clear colorless to slightly yellow liquid
The Uses of 4-Methoxyphenethylamine
4-Methoxyphenethylamine an inhibitor of the deamination of tyramine and tryptamine. It is intermediates of ritodrine. ritodrine is an adrenergic β2 receptor agonists used to prevent premature birth.
What are the applications of Application
4-Methoxyphenethylamine was used in the synthesis of :
pyrrolo[3,2-c]carbazole
poly(4-methoxyphenethylamine), required for the immobilization of nitrogenated bases and oligonucleotides
organopolyphosphazenes such as poly[bis(4-methoxy benzylamino)polyphosphazene] and poly[bis(4-methoxyphenethylamino)polyphosphazene]
4-methoxyphenethylamine was reacted with CDI and obtained N-substituted imidazolide intermediate.
What are the applications of Application
2-(4-Methoxyphenyl)ethylamine is an inhibitor of the deamination of tyramine and tryptamine
Definition
ChEBI: 4-methoxyphenylethylamine is a primary amino compound consisting of ethylamine having a 4-methoxyphenyl substituent at the 2-position. It derives from a hydride of a 2-phenylethylamine.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 15, p. 214, 1972 DOI: 10.1021/jm00272a029
General Description
4-Methoxyphenethylamine inhibits the monoamine oxidase-catalyzed deamination of both tyramine and tryptamine.
Properties of 4-Methoxyphenethylamine
| Melting point: | 249-251°C |
| Boiling point: | 138-140 °C20 mm Hg(lit.) |
| Density | 1.031 g/mL at 20 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | 9.96±0.10(Predicted) |
| form | liquid |
| color | light yellow |
| BRN | 508967 |
| CAS DataBase Reference | 55-81-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzeneethanamine, 4-methoxy-(55-81-2) |
| EPA Substance Registry System | Benzeneethanamine, 4-methoxy- (55-81-2) |
Safety information for 4-Methoxyphenethylamine
| Signal word | Danger |
| Pictogram(s) |
![]() Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 4-Methoxyphenethylamine
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