4-METHOXYPHENETHYL ALCOHOL
Synonym(s):2-(4-Methoxyphenyl)ethanol
- CAS NO.:702-23-8
- Empirical Formula: C9H12O2
- Molecular Weight: 152.19
- MDL number: MFCD00002900
- EINECS: 211-866-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 4-METHOXYPHENETHYL ALCOHOL?
Chemical properties
clear light brown liquid after melting
The Uses of 4-METHOXYPHENETHYL ALCOHOL
4-Methoxyphenethyl alcohol has a flavor and aroma of fresh citrus juice and may be used for perfumes, foods, and cosmetics.
The Uses of 4-METHOXYPHENETHYL ALCOHOL
2-(4-Methoxyphenyl)ethanol is used as an internal standard in the fluorous biphasic catalysis reaction. It is used in the preparation of 4-(2-iodoethyl)phenol, by refluxing it with 47% hydriodic acid. It may be used in the preparation of (2R*,4R*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline and (2R*,4S*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4- tetrahydroquinoline. It is used for foods, perfumes, and cosmetics.
The Uses of 4-METHOXYPHENETHYL ALCOHOL
4-Methoxyphenethyl alcohol was used in the preparation of 4-(2-iodoethyl)phenol, by refluxing it with 47% hydriodic acid. It may be used in the preparation of (2R*,4R*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline and (2R*,4S*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4- tetrahydroquinoline.
What are the applications of Application
2-(4-Methoxyphenyl)ethanol is A chemical exhibiting aroma and flavor of fresh citrus juice
Synthesis Reference(s)
Journal of the American Chemical Society, 82, p. 3222, 1960 DOI: 10.1021/ja01497a062
Tetrahedron Letters, 33, p. 7465, 1992 DOI: 10.1016/S0040-4039(00)60796-7
General Description
(R)-1-(4-methoxyphenyl)ethanol {(R)-MOPE, 4-Methoxyphenethyl alcohol, 1-(4-methoxyphenyl)ethanol } is formed during the biocatalytic anti-Prelog enantioselective reduction of 4-methoxyacetophenone (MOAP) using immobilized Trigonopsis variabilis AS2.
Properties of 4-METHOXYPHENETHYL ALCOHOL
| Melting point: | 26-28 °C(lit.) |
| Boiling point: | 334-336 °C(lit.) |
| Density | 1.058±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.536-1.538 |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in DMSO, Methanol. |
| form | Liquid After Melting |
| pka | 15.00±0.16(Predicted) |
| color | Clear light brown |
| FreezingPoint | 23.0 to 28.0 ℃ |
| BRN | 2043563 |
| CAS DataBase Reference | 702-23-8(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Methoxybenzeneethanol (702-23-8) |
Safety information for 4-METHOXYPHENETHYL ALCOHOL
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 4-METHOXYPHENETHYL ALCOHOL
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