4-Methoxy-3-hydroxyacetophenone
Synonym(s):1-(3-hydroxy-4-methoxyphenyl)ethanone
- CAS NO.：6100-74-9
- Empirical Formula: C9H10O3
- Molecular Weight: 166.17
- MDL number: MFCD00182975
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:03
What is 4-Methoxy-3-hydroxyacetophenone?
Chemical properties
solid
The Uses of 4-Methoxy-3-hydroxyacetophenone
Isoacetovanillone is a volatile compound isolated from oak wood. Also a byproduct in the production of Acetovanillone.
The Uses of 4-Methoxy-3-hydroxyacetophenone
Isoacetovanillone (Diosmin EP Impurity A) is a volatile compound isolated from oak wood. Also a byproduct in the production of Acetovanillone.
Preparation
Preparation by saponification of 3-acetoxy-4-methoxy-acetophenone (90%) (59%).
Definition
ChEBI: Isoacetovanillone is a member of phenols and a member of methoxybenzenes. It has a role as a metabolite.
Synthesis Reference(s)
Synthetic Communications, 18, p. 1379, 1988 DOI: 10.1080/00397918808078806
Properties of 4-Methoxy-3-hydroxyacetophenone
| Melting point: | 88-92 °C |
| Boiling point: | 329.9±27.0 °C(Predicted) |
| Density | 1.158 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.15±0.10(Predicted) |
| color | Off-White to Yellow |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
Safety information for 4-Methoxy-3-hydroxyacetophenone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Methoxy-3-hydroxyacetophenone
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