4-Hydroxybenzhydrazide
Synonym(s):p-Hydroxybenzoic acid hydrazide;4-Hydroxybenzhydrazide;4-Hydroxybenzoic hydrazide;4-Hydroxybenzoylhydrazine
- CAS NO.：5351-23-5
- Empirical Formula: C7H8N2O2
- Molecular Weight: 152.15
- MDL number: MFCD00007605
- EINECS: 226-326-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:13
What is 4-Hydroxybenzhydrazide?
Chemical properties
white to slightly beige fine crystalline powder
The Uses of 4-Hydroxybenzhydrazide
4-Hydroxybenzhydrazide is a reagent for the rapid automated determination of serum glucose.It can be used as an indicator for the determination of carbohydrates. The acid-hydrolyzable side chains of tissue (liver) bound 4-Hydroxybenzhydrazide can be used as markers to monitor its residues in chickens.
The Uses of 4-Hydroxybenzhydrazide
4-Hydroxybenzhydrazide has been used:
for determining the concentration of maltose from starch digestion
for analysis of sugars from fructan containing food hydrolysate
in colorimetric assay for reducing sugar estimation from processed feedstuff
Biochem/physiol Actions
4-Hydroxybenzhydrazide (PAHBAH), is used for assaying α-amylase and glucoamylase activities. The assay based on PAHBAH measures non-specifically the free reducing sugar groups present in samples at 415nm colorimetrically.
Properties of 4-Hydroxybenzhydrazide
| Melting point: | 264-266 °C (dec.)(lit.) |
| Boiling point: | 274.61°C (rough estimate) |
| Density | 1.2804 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | Store at +15°C to +25°C. |
| solubility | 26.5g/l |
| pka | 8.57±0.15(Predicted) |
| form | Fine Crystalline Powder |
| color | White to slightly beige |
| λmax | 245nm(MeOH)(lit.) |
| BRN | 473052 |
| CAS DataBase Reference | 5351-23-5(CAS DataBase Reference) |
| NIST Chemistry Reference | P-hydroxybenzoic acid, hydrazide(5351-23-5) |
Safety information for 4-Hydroxybenzhydrazide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Hydroxybenzhydrazide
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![2,3-DICHLORO-4-[2-(4-METHOXYBENZOYL)HYDRAZONO]BUT-2-ENOIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB9665828.gif)
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