4-HYDROXY-4-PHENYLPIPERIDINE
Synonym(s):4-Phenyl-4-piperidinol
- CAS NO.:40807-61-2
- Empirical Formula: C11H15NO
- Molecular Weight: 177.24
- MDL number: MFCD00006000
- EINECS: 255-089-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 4-HYDROXY-4-PHENYLPIPERIDINE?
The Uses of 4-HYDROXY-4-PHENYLPIPERIDINE
Reactant for synthesis of:
- Diaminotriazine hNav1.7 inhibitors
- Selective σ?ligands
- Glycogen synthase kinase-3β?inhibitors
- Diphenylbutylpiperidines as cell autophagy inducers
- Malonyl-coA decarboxylase inhibitors with antiobesity and antidiabetic activities
- Selective dopamine D2 receptor antagonists
Synthesis Reference(s)
Journal of the American Chemical Society, 78, p. 1702, 1956 DOI: 10.1021/ja01589a060
Properties of 4-HYDROXY-4-PHENYLPIPERIDINE
| Melting point: | 157-161 °C(lit.) |
| Boiling point: | 317.9±42.0 °C(Predicted) |
| Density | 1.093 |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 14.13±0.20(Predicted) |
| color | Pale brown |
| BRN | 141577 |
| CAS DataBase Reference | 40807-61-2(CAS DataBase Reference) |
Safety information for 4-HYDROXY-4-PHENYLPIPERIDINE
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 4-HYDROXY-4-PHENYLPIPERIDINE
| InChIKey | KQKFQBTWXOGINC-UHFFFAOYSA-N |
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