4-Fluorobenzyl bromide

Synonym(s):α-Bromo-4-fluorotoluene;1-Bromomethyl-4-fluorobenzene

CAS NO.：459-46-1
Empirical Formula: C7H6BrF
Molecular Weight: 189.02
MDL number: MFCD00000359
EINECS: 207-291-5
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-25 17:15:13

What is 4-Fluorobenzyl bromide?

Chemical properties

Colorless to light yellow liqui

The Uses of 4-Fluorobenzyl bromide

4-Fluorobenzyl bromide was used in the preparation of:

3-acetyl-1-(4-fluorobenzyl)-4-hydroxy-1H-indole
1-(4-fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isatin
(S)-1-(4-fluorobenzyl)-5-(2-(4-fluorophenoxymethyl)pyrrolidine-1-sulfonyl)isatin
8-bromo 9-(4-fluorobenzyl) adenine
8-bromo 3-(4-fluorobenzyl) adenine

The Uses of 4-Fluorobenzyl bromide

4-Fluorobenzyl Bromide is a substituted benzyl bromide reagent used in the preparation of wide range of biologically active compounds such as bronchodialators, neurochemicals and antibacterials.

What are the applications of Application

4-Fluorobenzyl bromide is a versatile fluorobenzene starting reagent

Properties of 4-Fluorobenzyl bromide

Boiling point:	85 °C15 mm Hg(lit.)
Density	1.517 g/mL at 25 °C(lit.)
refractive index	n20/D 1.547(lit.)
Flash point:	>230 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Chloroform
form	Liquid
color	Clear colorless to yellow
Specific Gravity	1.517
Sensitive	Lachrymatory
BRN	636507
CAS DataBase Reference	459-46-1(CAS DataBase Reference)
NIST Chemistry Reference	«alpha»-Bromo-4-fluorotoluene(459-46-1)
EPA Substance Registry System	4-Fluorobenzyl bromide (459-46-1)

Safety information for 4-Fluorobenzyl bromide

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.