4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Synonym(s):(4R,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride;4-Epianhydrotetracycline hydrochloride
- CAS NO.：4465-65-0
- Empirical Formula: C22H22N2O7.ClH
- Molecular Weight: 462.88
- MDL number: MFCD00151455
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-19 15:07:56
What is 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE?
Chemical properties
orange powder
The Uses of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity.
The Uses of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study.
What are the applications of Application
4-Epianhydrotetracycline Hydrochloride is the epi- derivative of Tetracycline
Properties of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
| Melting point: | 220 °C |
| storage temp. | -20°C Freezer |
| solubility | DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml |
| form | Powder |
| color | Orange |
| BRN | 3840711 |
| EPA Substance Registry System | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0) |
Safety information for 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Computed Descriptors for 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
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