4-Chlorophenethylamine
Synonym(s):4-Chlorophenethylamine
- CAS NO.:156-41-2
- Empirical Formula: C8H10ClN
- Molecular Weight: 155.62
- MDL number: MFCD00008191
- EINECS: 205-853-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:03
What is 4-Chlorophenethylamine?
Chemical properties
Dark Solid
The Uses of 4-Chlorophenethylamine
2-(4-Chlorophenyl)ethylamine has been used as a reactant in the preparation of isoalloxazine derivatives as cholinesterase inhibitors with a potential use in Alzheimer therapy.
Description
4-Chlorophenethylamine(CPA) is a synthetic serotonergic amine that has inhibitory activities. It is able to bind with the 5-HT receptor, which is also known as the serotonin receptor. CPA has been shown to be an anticancer compound and can be used in experimental solubility studies. This drug binds to brain cells, but does not affect their viability.
Chemical reactions
4-Chlorophenethylamine(CPA) hydrolyzes in the presence of hydrochloric acid or hydrogen chloride to produce 2-(4-chlorophenyl)ethanol (CPE). The reaction of CPA with serotonin produces 4-chloroamphetamine (PCA), which is a stimulant drug.
Properties of 4-Chlorophenethylamine
| Boiling point: | 60-65 °C0.1 mm Hg(lit.) |
| Density | 1.112 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 223 °F |
| storage temp. | Store Cold |
| form | Liquid |
| pka | 9.72±0.10(Predicted) |
| Specific Gravity | 1.12 |
| color | Clear colorless to yellow |
| BRN | 508247 |
| CAS DataBase Reference | 156-41-2(CAS DataBase Reference) |
Safety information for 4-Chlorophenethylamine
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Chlorophenethylamine
| InChIKey | SRXFXCKTIGELTI-UHFFFAOYSA-N |
4-Chlorophenethylamine manufacturer
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