4'-CHLORODIAZEPAM
Synonym(s):4ʹ-chlorodiazepam, TSPO Activator I, Mitochondrial Translocator Protein Activator I, Ro54864;7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one;Ro 5-4864;Ro5-4864;TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem
- CAS NO.：14439-61-3
- Empirical Formula: C16H12Cl2N2O
- Molecular Weight: 319.19
- MDL number: MFCD00043406
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:08
What is 4'-CHLORODIAZEPAM?
The Uses of 4'-CHLORODIAZEPAM
4′-Chlorodiazepam has been used as a translocator protein ligand in mitochondrial functional studies. It has also been used to investigate its protective effects on glucose deprived T98G astrocyte cell lines.
Biochem/physiol Actions
4′-Chlorodiazepam (Ro5-4864) is a potent selective ligand for the mitochondrial translocator protein 18kDa (TSPO), formerly known as the peripheral benzodiazepine receptor (PBR). Ro5-4864 does not bind to GABA(A) receptors and lacks typical benzodiazepine effects, but has been found to be neuroprotective in several studies.
Properties of 4'-CHLORODIAZEPAM
| Melting point: | 160-163 °C |
| Boiling point: | 517.1±50.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | +2C to +8C |
| solubility | ethanol: 17 mg/mL |
| form | Off-white powder |
| pka | 3.08±0.10(Predicted) |
| color | White to light yellow |
| BRN | 685202 |
Safety information for 4'-CHLORODIAZEPAM
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for 4'-CHLORODIAZEPAM
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 1-AMino-cyclobutaneMethanol HCl TETRABUTYLAMMONIUM CYANIDE 3-Amino-3-(3-fluorophenyl)propanoic acid 3-Amino-3-(4-methylphenyl)propionic acid 3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-amino-5-nitrobenzonitrile (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanideRelated products of tetrahydrofuran
![1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE](https://img.chemicalbook.in/CAS/GIF/3034-65-9.gif)
You may like
-
4′-Chlorodiazepam solution CAS 14439-61-3View Details
14439-61-3 -
4′-Chlorodiazepam CAS 14439-61-3View Details
14439-61-3 -
TSPO Agonist, Ro5-4864 CAS 14439-61-3View Details
14439-61-3 -
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
68208-21-9 98+View Details
68208-21-9 -
3-Amino-3-(3-fluorophenyl)propanoic acid 98+View Details
117391-51-2 -
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4 98+View Details
68208-18-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.