4-Chlorobenzyl bromide
- CAS NO.：622-95-7
- Empirical Formula: C7H6BrCl
- Molecular Weight: 205.48
- MDL number: MFCD00040714
- EINECS: 210-760-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-04 16:00:12
What is 4-Chlorobenzyl bromide?
Chemical properties
White crystalline low melting solid
The Uses of 4-Chlorobenzyl bromide
4-Chlorobenzyl bromide is used as pharmaceutical intermediate.
The Uses of 4-Chlorobenzyl bromide
4-Chlorobenzyl bromide may be used to synthesize 1-(4-chlorobenzyl)-2-(pyrrolidin-1-yl-methyl)-1H-benzimidazole dihydrochloride
General Description
4-Chlorobenzyl bromide undergoes carbonylation in the presence of dimer of chloro(1,5-cyclooctadiene)rhodium(I) to yield the corresponding phenylacetic acid. It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.
Properties of 4-Chlorobenzyl bromide
| Melting point: | 48-52 °C (lit.) |
| Boiling point: | 107-108°C 8mm |
| Density | 1.570±0.06 g/cm3(Predicted) |
| Flash point: | >230 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform, Dichloromethane (Slightly) |
| form | Crystalline Low Melting Solid |
| color | White |
| Water Solubility | Insoluble in water. |
| Sensitive | Lachrymatory |
| BRN | 606497 |
| CAS DataBase Reference | 622-95-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Chlorobenzyl bromide(622-95-7) |
Safety information for 4-Chlorobenzyl bromide
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Chlorobenzyl bromide
| InChIKey | KQNBRMUBPRGXSL-UHFFFAOYSA-N |
4-Chlorobenzyl bromide manufacturer
New Products
1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one Cis-Tosylate Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D BENZENE-D6 TOLUENE-D3 2-Hydroxybutanenitrile 1-Benzylindolin-2-one Ethyl 2-bromo-3-oxobutanoate 4-(3-chloropropyl)morpholine 1-Benzylindoline-2,3-dione 3-Oxocyclobutanecarboxylic acid 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
622-95-7 98%View Details
622-95-7 -
4-Chlorobenzyl Bromide CAS 622-95-7View Details
622-95-7 -
4-Chlorobenzyl bromide CAS 622-95-7View Details
622-95-7 -
4-Chlorobenzyl bromide 622-95-7 99.10%View Details
622-95-7 -
622-95-7 99%View Details
622-95-7 -
5-Bromo-2-chloro- benzoic acid 21739-92-4 98%View Details
21739-92-4 -
52092-43-0 2-Bromo-4-nitropyridine-N-oxide 98%View Details
52092-43-0 -
68886-07-7 98%View Details
68886-07-7
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.