4-Chloro-2-nitrotoluene
- CAS NO.：89-59-8
- Empirical Formula: C7H6ClNO2
- Molecular Weight: 171.58
- MDL number: MFCD00007215
- EINECS: 201-921-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-04 16:00:12
What is 4-Chloro-2-nitrotoluene?
Chemical properties
clear brown liquid after melting
The Uses of 4-Chloro-2-nitrotoluene
4-Chloro-2-nitrotoluene can be used in the synthesis of indigo dye.
The Uses of 4-Chloro-2-nitrotoluene
4-Chloro-1-methyl-2-nitrobenzene is used in the synthesis of NMDA-glycine antagonists. Also it is used in the preparation of COX-2 inhibitor.
Production Methods
4-Chlorotoluene is nitrated with mixed acid (39/59/2) at 25 ℃ to give a mixture of 4-Chloro-2-nitrotoluene (65 %) and 4-Chloro-3-nitrotoluene (35 %) isomers. The major component is separated as the lower boiling fraction on vacuum distillation. 4-Chloro-3-nitrotoluene [89-60-1] can be obtained, if required, from the residue by distillation and sweating.
Biochem/physiol Actions
4-Chloro-2-nitrotoluene is the starting reagent for synthesis of tricyclic indole-2-carboxylic acids, a potential NMDA-glycine antagonists.
Properties of 4-Chloro-2-nitrotoluene
| Melting point: | 34-38 °C (lit.) |
| Boiling point: | 239-240 °C/718 mmHg (lit.) |
| Density | 1.2559 |
| refractive index | 1.5570 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| form | powder to lump to clear liquid |
| color | White or Colorless to Yellow |
| Water Solubility | 109 mg/L (20 ºC) |
| BRN | 2046651 |
| CAS DataBase Reference | 89-59-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Chloro-2-nitrotoluene(89-59-8) |
| EPA Substance Registry System | Benzene, 4-chloro-1-methyl-2-nitro- (89-59-8) |
Safety information for 4-Chloro-2-nitrotoluene
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07  Health Hazard GHS08  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H373:Specific target organ toxicity, repeated exposure H401:Hazardous to the aquatic environment, acute hazard H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 4-Chloro-2-nitrotoluene
4-Chloro-2-nitrotoluene manufacturer
SAKEM LLP
1Y
Phone:+91-9676889998
Whatsapp: +91-9676889998
product: 4-Chloro-2-nitrotoluene 89-59-8 98%
New Products
6-Hydroxy-2,4-Diaminopyrimidine 2,6-Dipicolic Acid 3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID 4-Fluorophenylglycine 1-N-Boc-3-(aminoethyl)azetidine Dimedone 1-Boc-3-(cyanomethyl)azetidine N-BOC-piperidine-4-carboxylic acid 2-Amino-5-Bromo Pyridine 2-Amino-5-Iodopyridine 2,5-Dibromopyridine METHANOL-D1(OD) 3-BROMO PYRIDINE-D4 2-BROMOACETYL BROMIDE-D2 DEUTERIUM OXIDE FOR NMR BENZENE-D6 TOLUENE-D3 5-Acetylsalicylamide 1-(3-Chlorophenyl)-4-(3-Chloropropyl) piperazine hydrochloride 4-(Methyl amino)-3-Nitro benzoic acid 3,4,5-Trimethoxy benzoic acidRelated products of tetrahydrofuran
You may like
-
89-59-8 4-CHLORO-2-NITRO TOLUENE 98%View Details
89-59-8 -
4-Chloro-2-nitrotoluene, 99% 89-59-8 99%View Details
89-59-8 -
2-Chloro-4-nitrotoluene, 98% CAS 89-59-8View Details
89-59-8 -
4-Chloro-2-nitrotoluene CAS 89-59-8View Details
89-59-8 -
4-Chloro-2-nitrotoluene 89-59-8 98%View Details
89-59-8 -
1-(4-Aminophenyl)-4-(4-methoxyphenyl)Piperazine 74852-62-3View Details
74852-62-3 -
556-08-1 4-Acetamidobenzoic acidView Details
556-08-1 -
5-Bromo-2-Chlorobenzoic acid 21739-92-4View Details
21739-92-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.