4-Bromomethylbenzoic acid
Synonym(s):α-Bromo-p-toluic acid;α-Bromo-p-toluylic acid;4-(Bromomethyl)benzoic acid
- CAS NO.：6232-88-8
- Empirical Formula: C8H7BrO2
- Molecular Weight: 215.04
- MDL number: MFCD00002567
- EINECS: 228-343-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:27
What is 4-Bromomethylbenzoic acid?
Chemical properties
white to beige crystalline powder
The Uses of 4-Bromomethylbenzoic acid
4-(Bromomethyl)benzoic acid was used in the chemical modification of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), second generation photosensitizer. It was also used in the synthesis of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.
The Uses of 4-Bromomethylbenzoic acid
4-(Bromomethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive agent.
The Uses of 4-Bromomethylbenzoic acid
4-(Bromomethyl)benzoic acid acts as an intermediate in the synthesis of eprosartan, which is used as an antihypertensive agent. Further, it is used in the preparation of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), which is a second generation photosensitizer. In addition to this, it is used in the preparation of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.
Purification Methods
Crystallise the acid from pKEst Me2CO. [Beilstein 9 IV 1745.]
Properties of 4-Bromomethylbenzoic acid
| Melting point: | 224-229 °C(lit.) |
| Boiling point: | 252.95°C (rough estimate) |
| Density | 1.5313 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Store below +30°C. |
| pka | 4.10±0.10(Predicted) |
| form | Crystalline Powder |
| color | White to beige |
| Water Solubility | Soluble in water. |
| BRN | 1862870 |
| CAS DataBase Reference | 6232-88-8(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 4-(bromomethyl)- (6232-88-8) |
Safety information for 4-Bromomethylbenzoic acid
| Signal word | Warning |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P309:IF exposed or if you feel unwell: P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 4-Bromomethylbenzoic acid
| InChIKey | CQQSQBRPAJSTFB-UHFFFAOYSA-N |
4-Bromomethylbenzoic acid manufacturer
INNOVATIVE LABS
1Y
Phone:+91-9885794886
Whatsapp: +91-9885794886
product: 6232-88-8 4-Bromomethylbenzoicacid 99%
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: 4-Bromomethyl-benzoic acid
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran
You may like
-
4-BROMOMETHYL BENZOIC ACID 6232-88-8 98%View Details
6232-88-8 -
4-Bromomethyl-benzoic acid 6232-88-8 98%View Details
6232-88-8 -
4-Bromomethylbenzoic acid 98%View Details
6232-88-8 -
4-(Bromomethyl)benzoic acid CAS 6232-88-8View Details
6232-88-8 -
4-(Bromomethyl)benzoic Acid CAS 6232-88-8View Details
6232-88-8 -
Eprosartan Related Compound D CAS 6232-88-8View Details
6232-88-8 -
6232-88-8 98%View Details
6232-88-8 -
6232-88-8 4-Bromomethylbenzoicacid 99%View Details
6232-88-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.