4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
- CAS NO.：88404-25-5
- Empirical Formula: C12H11BrO4
- Molecular Weight: 299.12
- MDL number: MFCD00011570
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:00
What is 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN?
Chemical properties
Light Greenish-Yellow Powder
The Uses of 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
4-Bromomethyl-6,7-dimethoxycoumarin was used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It was also used as derivatization reagent:
- for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography
- in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
- for determination of carboxylic acids in chromatographic detection
The Uses of 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
A fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids
The Uses of 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
4-Bromomethyl-6,7-dimethoxycoumarin is used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It is also used as derivatization reagent: for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography, in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry and for determination of carboxylic acids in chromatographic detection.
What are the applications of Application
4-(Bromomethyl)-6,7-dimethoxycoumarin is an HPLC fluorescent labeling reagent
Properties of 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
| Melting point: | 212-216 °C(lit.) |
| Density | 1.6176 (rough estimate) |
| refractive index | 1.4490 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Soluble in acetonitrile, dichloromethane,
N,N-dimethylformamide, methanol |
| form | Powder |
| color | Yellow crystals or powder |
| Water Solubility | Insoluble in water. |
| λmax | 348 nm (MeOH) |
| BRN | 4750487 |
| Major Application | Electrostatic imaging
process; resists; printed circuit boards;
semiconductor devices |
| Biological Applications | Analyzing bile
acid; anticancer agents; identifying bacteria;
identifying/measuring lauric acid metabolites;
measuring cyclosporine; studying/monitoring early
stages of protein folding;treating gastrointestinal
diseases; derivatization reagent for carboxylic
acids; as a substrate for measuring lauric acid
hydroxylase activity |
| CAS DataBase Reference | 88404-25-5(CAS DataBase Reference) |
Safety information for 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
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