4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
- CAS NO.：757251-39-1
- Empirical Formula: C13H12FN3O2
- Molecular Weight: 261.25
- MDL number: MFCD09033852
- EINECS: 692-721-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:52
What is 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE?
Chemical properties
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide has the appearance of a white to yellow powder or crystals, which is stable and non-reactive under normal conditions of use, storage and transport.
The Uses of 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.
Definition
ChEBI: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide is an aromatic ether.
Properties of 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
| Melting point: | 143 °C |
| Boiling point: | 459.8±45.0 °C(Predicted) |
| Density | 1.305 |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 13.92±0.46(Predicted) |
| color | Orange to Dark Red to Brown |
| Water Solubility | 190mg/L at 20℃ |
Safety information for 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE manufacturer
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product: 757251-39-1 95.00%
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