3,5-Difluorophenylboronic acid
Synonym(s):(3,5-Difluorophenyl)dihydroxyborane;3,5-Difluorobenzeneboronic acid
- CAS NO.：156545-07-2
- Empirical Formula: C6H5BF2O2
- Molecular Weight: 157.91
- MDL number: MFCD01318138
- EINECS: 605-060-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:13
What is 3,5-Difluorophenylboronic acid?
Chemical properties
White to beige-yellowish powder
The Uses of 3,5-Difluorophenylboronic acid
3,5-Difluorophenylboronic Acid is used in the synthesis of N-thiazol-2-yl-benzamides as glucokinase (GK) activators for treatment of type 2 diabetes mellitus (T2DM).
The Uses of 3,5-Difluorophenylboronic acid
Reactant involved in:• ;Synthesis of honokiol analogs as angiogenesis inhibitors1• ;Homo-coupling reactions2• ;Suzuki-Miyaura cross-coupling reactions3• ;Enantioselective borane reduction of trifluoroacetophenone4
Properties of 3,5-Difluorophenylboronic acid
| Melting point: | 210-217 °C (lit.) |
| Boiling point: | 266.9±50.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder |
| pka | 6.46±0.10(Predicted) |
| color | White to Orange to Green |
| BRN | 6800882 |
| CAS DataBase Reference | 156545-07-2(CAS DataBase Reference) |
Safety information for 3,5-Difluorophenylboronic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,5-Difluorophenylboronic acid
New Products
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