3,5-Difluorobenzoic acid
- CAS NO.：455-40-3
- Empirical Formula: C7H4F2O2
- Molecular Weight: 158.1
- MDL number: MFCD00010323
- EINECS: 610-261-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:24
What is 3,5-Difluorobenzoic acid?
Chemical properties
off-white needles and chunks
The Uses of 3,5-Difluorobenzoic acid
3,5-Difluorobenzoic Acid can be used as reactant/reagent in Rh(III)-catalyzed regioselective heterocyclization of benzoic acids with acrylates to give phthalides with water as the solvent
General Description
3,5-Difluorobenzoic acid forms dimers that were stabilized by hydrogen bonds between carboxyl groups. The on-line determination of 3,5-difluorobenzoic acid in water was studied using membrane inlet mass spectrometry with in-membrane preconcentration.
Properties of 3,5-Difluorobenzoic acid
| Melting point: | 121-123 °C (lit.) |
| Boiling point: | 243.2±20.0 °C(Predicted) |
| Density | 1.3486 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Soluble), Methanol (Slightly) |
| form | Solid |
| pka | 3.52±0.10(Predicted) |
| color | White to Pale Yellow |
| BRN | 1940680 |
| CAS DataBase Reference | 455-40-3(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 3,5-difluoro- (455-40-3) |
Safety information for 3,5-Difluorobenzoic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,5-Difluorobenzoic acid
| InChIKey | GONAVIHGXFBTOZ-UHFFFAOYSA-N |
New Products
5-Chlorothiophene-2-carboxylic acid 2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-3-methyl xanthine Maleic hydrazide 6-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridine 3,4-Dihydroxyacetophenone 3,4-Dimethoxyacetophenone 4-Nitroacetophenone DL-Glutamic acid 3-Nitroacetophenone 4'-Chloro-3'-nitroacetophenone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 1-Boc-4-cyanopiperidine 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 3-Hydroxy-2-methylbenzoic acid 1,3-Dibromo-5-fluorobenzene 2-((2,6-Difluorobenzyl)(ethoxycarbonyl)amino)-4-((dimethylamino)methyl)-5-(4-nitrophenyl)thiophene-3-carboxylic acid [N(E)]-N-Ethylidene-2-methyl-2-propanesulfinamide 4-Isopropyl Thiophenol 6-(chloromethyl)pteridine-2,4-diamine monohydrochloride 2-Chlorophenyl diphenyl chloromethaneRelated products of tetrahydrofuran
You may like
-
3,5-Difluorobenzoic Acid CAS 455-40-3View Details
455-40-3 -
586-37-8 98+View Details
586-37-8 -
1-Boc-Azetidine-3-yl-methanol 98+View Details
142253-56-3 -
4-Nitroacetophenone 100-19-6 98+View Details
100-19-6 -
1197-09-7' 98+View Details
1197-09-7' -
3,4-Dimethoxyacetophenone 98+View Details
1131-62-0 -
4-Acetylbiphenyl 92-91-1 98+View Details
92-91-1 -
99-93-4 98+View Details
99-93-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.