3,4-Dihydroxy-N-methyl-N-nitrosoaniline
Synonym(s):3,4-Dihydroxy-N-methyl-N-nitrosoaniline
- Empirical Formula: C7H8N2O3
- Molecular Weight: 168.15
- MDL number: MFCD01076450
- Update Date: 2026-09-12 18:53:35
What is 3,4-Dihydroxy-N-methyl-N-nitrosoaniline?
The Uses of 3,4-Dihydroxy-N-methyl-N-nitrosoaniline
Methyl-3,4-dephostatin has been used as:
- an inhibitor for methyltransferases
- a kinase-related inhibitor for human transglutaminase
- a cysteine binding compound for screening its effect on C-terminal domain (CTD) of human immunodeficiency virus (HIV-1) capsid protein
What are the applications of Application
3,4-Dephostatin is a protein tyrosine phosphatase inhibitor
Biochem/physiol Actions
Methyl-3,4-dephostatin is a tyrphostin-related compound isolated from Streptomyces MJ742-NF5 strain. It favors nerve growth factor-based neurite formation in pheochromocytoma PC12 cells. Being a stable analog of the nitrosoaniline dephostatin, it can mimic phosphotyrosine substrate for Tyrosyl-DNA phosphodiesterase I (TdpI).
Properties of 3,4-Dihydroxy-N-methyl-N-nitrosoaniline
| storage temp. | 2-8°C |
| solubility | DMSO: 18 mg/mL, soluble |
| form | powder |
| color | red-brown |
Safety information for 3,4-Dihydroxy-N-methyl-N-nitrosoaniline
Computed Descriptors for 3,4-Dihydroxy-N-methyl-N-nitrosoaniline
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