3,4-Dichlorophenylacetonitrile
Synonym(s):3,4-Dichlorobenzyl cyanide
- CAS NO.：3218-49-3
- Empirical Formula: C8H5Cl2N
- Molecular Weight: 186.04
- MDL number: MFCD00001909
- EINECS: 221-743-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:05:31
What is 3,4-Dichlorophenylacetonitrile?
Chemical properties
WHITE CRYSTALLINE POWDER
The Uses of 3,4-Dichlorophenylacetonitrile
3,4-Dichlorophenylacetonitrile was used in the synthesis of:
- SR 48968, a potent, competitive and selective non-peptide antagonist of the neurokinin A (NK2) receptor
- tachykinin NK3 receptor antagonist SR 142801, (R)-N-[ 1-[3-[ 1-benzoyl-3-(3,4-dichlororphenyl)-3-piperidinyl]propyyl]-4-phenyl-4-piperidinyl-N-methyl acetamide
- MDL 105,212, a non-peptide tachykinin receptor antagonist
Properties of 3,4-Dichlorophenylacetonitrile
| Melting point: | 39-42 °C (lit.) |
| Boiling point: | 170 °C/12 mmHg (lit.) |
| Density | 1.4274 (rough estimate) |
| refractive index | 1.5690 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| color | White |
| BRN | 638749 |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| Stability: | Light Sensitive |
| CAS DataBase Reference | 3218-49-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 3,4-Dichlorophenylacetonitrile(3218-49-3) |
Safety information for 3,4-Dichlorophenylacetonitrile
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,4-Dichlorophenylacetonitrile
New Products
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