3,4-Dichlorobenzophenone

CAS NO.：6284-79-3
Empirical Formula: C13H8Cl2O
Molecular Weight: 251.11
MDL number: MFCD00000552
EINECS: 228-509-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:00:51

What is 3,4-Dichlorobenzophenone?

Chemical properties

light brown to pink-grey crystalline powde

The Uses of 3,4-Dichlorobenzophenone

3,4-Dichlorobenzophenone has been used as a reactant for the preparation of chiral benzyl alcohols.

Synthesis

The synthesis of 3,4-Dichlorobenzophenone is as follows:In around-bottom flask, diarylmethanes (1.0 mmol), NBS (889.9 mg, 5.0 mmol) andwater (0 or 5.0 mmol) were dissolved in CHCl3 (4.0 mL). After refluxing for 3 h in the air, the reaction mixture was quenched withNa2S2O3·5H2O, cooled to roomtemperature, washed with 5mL CH2Cl2, dried with MgSO4,and filtered to get clear organic solution. The solvent was removed reduced pressure by a rotary evaporator, and the resulting residue was subjected to column chromatography on silica gel using co-solvent(ethyl acetate / petroleum ether, v/v) as eluent to give the corresponding diaryllketones.
synthesis of 3,4-Dichlorobenzophenone

Properties of 3,4-Dichlorobenzophenone

Melting point:	100-103 °C
Boiling point:	356.37°C (rough estimate)
Density	1.2472 (rough estimate)
refractive index	1.5555 (estimate)
storage temp.	2-8°C
form	powder to crystal
color	White to Light yellow to Light orange
BRN	2105069
InChI	InChI=1S/C13H8Cl2O/c14-11-7-6-10(8-12(11)15)13(16)9-4-2-1-3-5-9/h1-8H
CAS DataBase Reference	6284-79-3(CAS DataBase Reference)

Safety information for 3,4-Dichlorobenzophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.