3,3-Diethoxypropionitrile

Chemical properties

CLEAR YELLOW TO BROWNISH LIQUID

The Uses of 3,3-Diethoxypropionitrile

3,3-Diethoxypropionitrile is a propionitrile derivative used in the preparation of various biologically active compounds such as p38α mitogen-activated protein kinase inhibitors.

The Uses of 3,3-Diethoxypropionitrile

3,3-Diethoxypropionitrile may be used in the synthesis of 2-(2,2-diethoxy-ethyl)-pyridine, via [2+2+2]-cycloaddition reaction. It may be used in the synthesis of cyanomalondialdehyde.

What are the applications of Application

3,3-Diethoxypropionitrile is used in the synthesis of 2-(2,2-diethoxy-ethyl)-pyridine

Synthesis Reference(s)

Journal of the American Chemical Society, 69, p. 2657, 1947 DOI: 10.1021/ja01203a028

General Description

3,3-Diethoxypropionitrile is a cyanide derivative. It undergoes reaction with urea in refluxing butanolic sodium butoxide to afford 4-amino-2(1H)-pyrimidinone and cytosine. Its physical properties (density, refractive index, boiling point and melting point) have been reported.