3-Phenylpropionic acid methyl ester

CAS NO.：103-25-3
Empirical Formula: C10H12O2
Molecular Weight: 164.2
MDL number: MFCD00017209
EINECS: 203-092-2
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-31 16:09:46

What is 3-Phenylpropionic acid methyl ester?

Description

Methyl 3-phenylpropionate has a strong floral-fruity odor. May be prepared by reduction of methyl cinnamate in methanol solution with hydrogen and Ni under pressure.

Chemical properties

Clear light yellow liquid

Chemical properties

Methyl-3-phenylpropionate has a strong floral–fruity odor, with honey and wine-like undertones

Occurrence

Reported found in tabasco peppers, grapes, rhubarb, soursop and basil

The Uses of 3-Phenylpropionic acid methyl ester

3-Phenylpropionic Acid Methyl Ester is an ester derivative of 3-phenylpropionic acid that is sometimes present in fragrance ingredients.

The Uses of 3-Phenylpropionic acid methyl ester

Methyl 3-phenylpropionate, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. 3-Phenylpropionic Acid Methyl Ester is an ester derivative of 3-phenylpropionic acid that is sometimes present in fragrance ingredients. It is also used as an application, aromatic intermediate.

Definition

ChEBI: Methyl 3-phenylpropanoate is a methyl ester resulting from the formal condensation of the carboxy group of 3-phenylpropionic acid with methanol. It has a role as a volatile oil component, a flavouring agent and a human metabolite. It is a methyl ester and a member of benzenes. It is functionally related to a 3-phenylpropionic acid.

Preparation

By reduction of methyl cinnamate in methanol solution with hydrogen and Ni under pressure

Aroma threshold values

Aroma characteristics at 1.0%: sweet, rich spicy Ceylon cinnamonlike, balsamic with fruity, resinous and powdery nuances

Taste threshold values

Taste characteristics at 5 ppm: cinnamon spicy, sweet, balsamic with fruity floral and resinous nuances.

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 5293, 1989 DOI: 10.1016/S0040-4039(01)93768-2
Journal of the American Chemical Society, 95, p. 625, 1973 DOI: 10.1021/ja00783a073

Properties of 3-Phenylpropionic acid methyl ester

Melting point:	142-145 °C
Boiling point:	91-92 °C4 mm Hg(lit.)
Density	1.043 g/mL at 25 °C(lit.)
refractive index	n20/D 1.502(lit.)
FEMA	2741 \| METHYL 3-PHENYLPROPIONATE
Flash point:	212 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Oil
color	Colourless to Pale Yellow
Odor	at 100.00 %. honey fruity wine balsam floral
Water Solubility	Soluble in chloroform. Insoluble in water.
JECFA Number	643
BRN	1909591
CAS DataBase Reference	103-25-3(CAS DataBase Reference)
NIST Chemistry Reference	3-Phenylpropanoic acid methyl ester(103-25-3)
EPA Substance Registry System	Benzenepropanoic acid, methyl ester (103-25-3)

Safety information for 3-Phenylpropionic acid methyl ester

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.