3-HYDROXYPYRAZINE-2-CARBOXAMIDE

CAS NO.：55321-99-8
Empirical Formula: C5H5N3O2
Molecular Weight: 139.11
MDL number: MFCD00233977
EINECS: 202-303-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:45:47

What is 3-HYDROXYPYRAZINE-2-CARBOXAMIDE?

Chemical properties

White crystalline powder

The Uses of 3-HYDROXYPYRAZINE-2-CARBOXAMIDE

Apart from biological importance of pyridine-2-carboxamide (picolinamide, pia) as well as of its derivatives such as 3-hydroxypyridine-2-carboxamide (3-OHpia), as ligands they have found their extensive application in coordina- tion chemistry in crystal engineering .

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 78, 1949 DOI: 10.1021/ja01169a023

Properties of 3-HYDROXYPYRAZINE-2-CARBOXAMIDE

Melting point:	ca 270℃
Density	1.63±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Aqueous Base (Slightly)
form	Solid
pka	10.69±0.40(Predicted)
color	Pale Brown to Brown
λmax	348nm(lit.)
Stability:	Hygroscopic

Safety information for 3-HYDROXYPYRAZINE-2-CARBOXAMIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.