(2-Hydroxypropyl)-γ-cyclodextrin
- CAS NO.：128446-34-4
- Empirical Formula: C48H80-nO40.(C3H7O)n
- Molecular Weight: 0
- MDL number: MFCD00148890
- EINECS: 207-166-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:14
What is (2-Hydroxypropyl)-γ-cyclodextrin?
Chemical properties
white powder
The Uses of (2-Hydroxypropyl)-γ-cyclodextrin
For R&D use
What are the applications of Application
(2-Hydroxypropyl)-γ-cyclodextrin is a gamma cyclodextrin that is a derivative of an 8-membered sugar ring molecule
General Description
(2-Hydroxypropyl)-γ-cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.
Properties of (2-Hydroxypropyl)-γ-cyclodextrin
| Melting point: | 52-55 °C(lit.) |
| Boiling point: | 97-98 °C3 mm Hg(lit.) |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | H2O: soluble450mg/mL |
| form | Solid powder |
| color | white |
| PH | 6-9 (2% in H2O) |
| optical activity | [α]20/D +145°, c = 1 in H2O |
| CAS DataBase Reference | 128446-34-4(CAS DataBase Reference) |
Safety information for (2-Hydroxypropyl)-γ-cyclodextrin
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (2-Hydroxypropyl)-γ-cyclodextrin
| InChIKey | WZMOWQCNPFDWPA-UHFFFAOYSA-N |
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